Diagnosis and Classification of Proteinuria

Diagnosis and Classification of Proteinuria

Daily urinary protein exceeds 150 mg or urinary protein/creatinine ratio (PCR) > 200 mg/g is called proteinuria. 24-hour urinary albumin excretion is called microalbuminuria in 30-300 mg.

Pathological proteinuria is more persistent and more:

1) Overflow proteinuria: The concentration of a certain protein in the plasma is too high and is filtered out by normal or abnormal glomeruli;

2) Renal globulinuria: glomerular filtration barrier damage;

3) Tubular proteinuria: Abnormal absorption of normal filtered proteins by renal tubules;

4) Tissue proteinuria: protein secreted by kidney tissue